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L Glutamine vs. Glutathione: Know the Difference

Shumaila Saeed
By Shumaila Saeed || Published on January 9, 2024
L-Glutamine is a non-essential amino acid important for muscle function and gut health; Glutathione is an antioxidant, protecting cells from damage.
L Glutamine vs. Glutathione

Key Differences

L-Glutamine is an amino acid, a building block of protein, important for muscle growth and maintenance. It plays a vital role in intestinal health and immune function. Glutathione, on the other hand, is a tripeptide, composed of three amino acids: cysteine, glutamine, and glycine. It is crucial for detoxification and as an antioxidant in protecting cells from oxidative stress.
Shumaila Saeed
Shumaila Saeed
Jan 09, 2024
In the human body, L-Glutamine is classified as a conditionally essential amino acid, meaning it becomes essential under certain conditions like stress or illness. Glutathione is a naturally occurring antioxidant, often referred to as the body's master antioxidant due to its central role in maintaining the redox balance within cells.
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Shumaila Saeed
Jan 09, 2024
L-Glutamine is commonly used as a supplement by athletes for muscle recovery and by individuals with gastrointestinal issues to support gut health. Glutathione is supplemented for its detoxifying properties, to support liver function, and for its anti-aging benefits, owing to its antioxidant properties.
Shumaila Saeed
Shumaila Saeed
Jan 09, 2024
In terms of synthesis, the body can produce L-Glutamine in sufficient quantities under normal conditions, but the demand increases during stress or illness. Glutathione, while synthesized by the body, can be depleted by factors like poor nutrition, stress, and environmental toxins, necessitating supplementation.
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Shumaila Saeed
Jan 09, 2024
Dietary sources differ for these two compounds. L-Glutamine is found in high-protein foods like meat, eggs, and dairy. Glutathione is found in foods rich in sulfur-containing amino acids, like garlic, onions, and cruciferous vegetables, but dietary intake directly contributes less to body levels compared to internal synthesis.
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Jan 09, 2024
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Comparison Chart

Type

Amino Acid
Tripeptide (Antioxidant)
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Jan 09, 2024

Function

Muscle maintenance, gut health
Detoxification, antioxidant
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Jan 09, 2024

Essentiality

Conditionally essential
Synthesized by the body
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Supplementation Use

Muscle recovery, gut health
Liver function, anti-aging
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Dietary Sources

Meat, eggs, dairy
Garlic, onions, cruciferous vegetables
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L Glutamine and Glutathione Definitions

L Glutamine

L-Glutamine is important for intestinal health.
L-Glutamine supplements are recommended for improving gut barrier function.
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Dec 28, 2023

Glutathione

Glutathione protects cells from oxidative stress.
Glutathione supplements are taken to reduce oxidative stress in the body.
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Dec 28, 2023

L Glutamine

L-Glutamine becomes essential in certain conditions.
In critical illness, L-Glutamine supplementation is often necessary.
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Dec 28, 2023

Glutathione

Glutathione has anti-aging properties.
Glutathione is popular in skincare for its anti-aging effects.
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L Glutamine

L-Glutamine is a key component in protein synthesis.
Bodybuilders consume L-Glutamine to aid in protein synthesis for muscle growth.
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Dec 28, 2023
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Glutathione

Glutathione aids in detoxifying the body.
Glutathione is used to support liver function and detoxification.
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L Glutamine

L-Glutamine supports muscle recovery post-exercise.
Athletes use L-Glutamine supplements for faster muscle recovery.
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Shumaila Saeed
Dec 28, 2023

Glutathione

Glutathione safeguards cells from damage.
Glutathione plays a key role in protecting cells during chemotherapy.
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L Glutamine

L-Glutamine boosts the immune system.
L-Glutamine is used to strengthen immunity in stressed individuals.
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Glutathione

Glutathione strengthens the immune system.
Glutathione supplements are used to boost immune health.
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Glutathione

A tripeptide, C10H17N3O6S, of glycine, cysteine, and glutamic acid that occurs widely in plant and animal tissues and is important in biological oxidation-reduction reactions.
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Glutathione

(biochemistry) A tripeptide formed from glutamic acid, cysteine and glycine, that is active in many biological redox reactions
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Repeatedly Asked Queries

What foods are high in L-Glutamine?

Foods rich in protein like meat, eggs, and dairy are high in L-Glutamine.
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Jan 09, 2024

What is L-Glutamine primarily used for?

L-Glutamine is used for muscle recovery and supporting gut health.
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Jan 09, 2024

Can L-Glutamine be produced by the body?

Yes, the body can produce L-Glutamine, but needs may increase during stress or illness.
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Can Glutathione be taken as a supplement?

Yes, Glutathione is available as a supplement for various health benefits.
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Can L-Glutamine help with intestinal issues?

Yes, L-Glutamine is beneficial for intestinal health and gut barrier function.
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Jan 09, 2024

Is L-Glutamine beneficial for athletes?

Yes, athletes use L-Glutamine for muscle recovery and immune support.
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Shumaila Saeed
Jan 09, 2024

Is Glutathione important for liver health?

Yes, Glutathione supports liver function and helps in detoxification.
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Shumaila Saeed
Jan 09, 2024

Does L-Glutamine aid in weight loss?

L-Glutamine can support weight loss efforts by promoting muscle mass and gut health.
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Can Glutathione improve skin health?

Yes, Glutathione is known for its benefits in skin health and is used in skincare products.
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Is L-Glutamine safe for long-term use?

Generally, L-Glutamine is safe for long-term use, but it's best to consult a healthcare provider.
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Shumaila Saeed
Jan 09, 2024

What is Glutathione's main function?

Glutathione is a potent antioxidant and is vital for detoxification.
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Can Glutathione help with chronic diseases?

Glutathione can be beneficial in managing chronic diseases due to its antioxidant properties.
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Jan 09, 2024

Is Glutathione effective against oxidative stress?

Yes, Glutathione effectively combats oxidative stress in the body.
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How does Glutathione affect aging?

Glutathione has anti-aging properties and can protect cells from damage.
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Jan 09, 2024

Which foods boost Glutathione levels?

Foods like garlic, onions, and cruciferous vegetables help boost Glutathione levels.
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Shumaila Saeed
Jan 09, 2024

Does cooking affect L-Glutamine content in food?

Yes, cooking can reduce the L-Glutamine content in foods.
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Jan 09, 2024

How does L-Glutamine benefit the immune system?

L-Glutamine supports the immune system by providing fuel for immune cells.
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Shumaila Saeed
Jan 09, 2024

Is L-Glutamine supplementation necessary for everyone?

L-Glutamine supplementation is not necessary for everyone, but can be beneficial under certain conditions.
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Shumaila Saeed
Jan 09, 2024

Does Glutathione interact with medications?

Glutathione can interact with some medications, so it's important to consult a healthcare provider.
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Jan 09, 2024

Are there any side effects of taking L-Glutamine?

L-Glutamine is generally well-tolerated, but high doses can cause digestive issues.
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Jan 09, 2024

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About Author
Shumaila Saeed
Written by
Shumaila Saeed
Shumaila Saeed, an expert content creator with 6 years of experience, specializes in distilling complex topics into easily digestible comparisons, shining a light on the nuances that both inform and educate readers with clarity and accuracy.

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