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Frontline Plus vs. Frontline Gold: Know the Difference

Shumaila Saeed
By Shumaila Saeed || Published on February 6, 2024
Frontline Plus is a monthly flea and tick treatment for pets, using fipronil and (S)-methoprene, while Frontline Gold adds a third ingredient, pyriproxyfen, for faster and broader protection.
Frontline Plus vs. Frontline Gold

Key Differences

Frontline Plus, a well-known flea and tick preventative for pets, primarily dogs and cats, has been a staple in pet care for many years. It contains two active ingredients: fipronil, which kills adult fleas and ticks, and (S)-methoprene, which attacks flea eggs and larvae. This combination effectively breaks the flea life cycle, helping to prevent future infestations. Frontline Plus is known for its effectiveness in controlling existing flea and tick infestations and providing protection for up to a month.
Shumaila Saeed
Shumaila Saeed
Feb 06, 2024
Frontline Gold, a more recent addition to the Frontline range, builds upon the formula of Frontline Plus. Like its predecessor, Frontline Gold contains fipronil and (S)-methoprene. However, it also includes a third ingredient, pyriproxyfen. This addition enhances the product's ability to kill fleas at all life stages more rapidly and provides a more comprehensive defense against flea and tick infestations. The inclusion of pyriproxyfen makes Frontline Gold a more advanced option for pet owners seeking extensive protection.
Shumaila Saeed
Shumaila Saeed
Feb 06, 2024
In terms of application, both Frontline Plus and Frontline Gold are applied topically, usually between the pet's shoulder blades, and are formulated to be waterproof. This means that pets can bathe or swim without diminishing the effectiveness of the treatment. The application process is designed to be simple and straightforward, ensuring ease of use for pet owners. However, due to the additional ingredient, Frontline Gold may offer a quicker onset of action compared to Frontline Plus.
Shumaila Saeed
Shumaila Saeed
Feb 06, 2024
Safety profiles of Frontline Plus and Frontline Gold are similar, with both products being well-tolerated by most pets. However, as with any medication, there can be individual sensitivities or reactions. It's always recommended to discuss with a veterinarian before starting any new flea and tick preventative, especially if the pet has a history of skin sensitivities or allergic reactions.
Shumaila Saeed
Shumaila Saeed
Feb 06, 2024
Finally, when deciding between Frontline Plus and Frontline Gold, pet owners should consider the level of infestation and their pet's specific needs. Frontline Plus remains a reliable choice for regular prevention, while Frontline Gold offers an enhanced level of protection, particularly useful in areas with high flea and tick populations or for pets with heightened exposure risks.
Shumaila Saeed
Shumaila Saeed
Feb 06, 2024
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Comparison Chart

Active Ingredients

Contains fipronil and (S)-methoprene.
Contains fipronil, (S)-methoprene, and pyriproxyfen.
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Shumaila Saeed
Feb 06, 2024

Efficacy

Effectively breaks the flea life cycle.
Offers faster action and broader protection against life stages.
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Shumaila Saeed
Feb 06, 2024

Application

Topical application, waterproof.
Topical application, waterproof.
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Shumaila Saeed
Feb 06, 2024

Onset of Action

Rapid onset, with full protection up to a month.
Quicker onset due to additional ingredient.
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Shumaila Saeed
Feb 06, 2024

Best Used For

Regular prevention of flea and tick infestations.
Enhanced protection in high-risk environments.
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Shumaila Saeed
Feb 06, 2024
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Frontline Plus and Frontline Gold Definitions

Frontline Plus

Frontline Plus is applied directly to the pet's skin.
Applying Frontline Plus is easy; just a few drops between the shoulder blades.
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Shumaila Saeed
Jan 20, 2024

Frontline Gold

Frontline Gold offers enhanced protection against fleas and ticks.
For our camping trips, I prefer using Frontline Gold for its advanced protection.
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Shumaila Saeed
Jan 20, 2024

Frontline Plus

Frontline Plus remains effective even after bathing.
I bathed my dog after applying Frontline Plus, and it still worked perfectly.
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Shumaila Saeed
Jan 20, 2024

Frontline Gold

Frontline Gold acts faster than traditional treatments.
After using Frontline Gold, I noticed a quicker reduction in fleas on my pet.
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Shumaila Saeed
Jan 20, 2024

Frontline Plus

Frontline Plus is a monthly treatment for fleas and ticks.
I use Frontline Plus monthly to keep my dog free from fleas and ticks.
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Shumaila Saeed
Jan 20, 2024
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Frontline Gold

Frontline Gold is used once a month for ongoing protection.
I apply Frontline Gold monthly for continuous flea and tick defense.
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Shumaila Saeed
Jan 20, 2024

Frontline Plus

Frontline Plus is administered once a month.
Every month, I remember to apply Frontline Plus to my cat to prevent fleas.
Shumaila Saeed
Shumaila Saeed
Jan 20, 2024

Frontline Gold

Frontline Gold is a simple, waterproof topical treatment.
Even after swimming, Frontline Gold stays effective on my dog.
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Shumaila Saeed
Jan 20, 2024

Frontline Plus

Frontline Plus combines fipronil and (S)-methoprene.
Frontline Plus's dual-action formula effectively eliminates fleas at all life stages.
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Shumaila Saeed
Jan 20, 2024

Frontline Gold

Frontline Gold includes fipronil, (S)-methoprene, and pyriproxyfen.
The triple-ingredient formula of Frontline Gold provides comprehensive flea control.
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Shumaila Saeed
Jan 20, 2024

Repeatedly Asked Queries

What is Frontline Plus used for?

Frontline Plus is a flea and tick preventative for dogs and cats.
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Shumaila Saeed
Feb 06, 2024

How often should Frontline Plus be applied?

Frontline Plus should be applied once a month.
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Shumaila Saeed
Feb 06, 2024

Is Frontline Gold also a monthly treatment?

Yes, Frontline Gold is applied monthly.
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Shumaila Saeed
Feb 06, 2024

Can Frontline Plus be used on puppies?

Frontline Plus is safe for puppies over 8 weeks old.
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Shumaila Saeed
Feb 06, 2024

What additional benefit does Frontline Gold offer?

Frontline Gold provides faster and broader protection against fleas and ticks.
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Shumaila Saeed
Feb 06, 2024

Is Frontline Gold suitable for kittens?

Frontline Gold can be used on kittens over 8 weeks and 1.5 pounds.
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Shumaila Saeed
Feb 06, 2024

How quickly does Frontline Gold act?

Frontline Gold starts killing fleas in just 30 minutes.
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Shumaila Saeed
Feb 06, 2024

Where can I buy Frontline Plus?

Available at vets, pet stores, and online retailers.
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Shumaila Saeed
Feb 06, 2024

What are the side effects of Frontline Gold?

Similar to Frontline Plus, skin irritation can occur.
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Shumaila Saeed
Feb 06, 2024

Is Frontline Gold safe for breeding animals?

Consult a vet, but it's typically safe for breeding animals.
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Shumaila Saeed
Feb 06, 2024

Does Frontline Plus work against ticks?

Yes, Frontline Plus is effective against ticks.
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Shumaila Saeed
Feb 06, 2024

How long does Frontline Plus take to work?

Frontline Plus starts killing fleas in 24-48 hours.
Shumaila Saeed
Shumaila Saeed
Feb 06, 2024

Are there any side effects of Frontline Plus?

Side effects are rare but can include skin irritation.
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Shumaila Saeed
Feb 06, 2024

Can Frontline Plus be used on pregnant pets?

Consult a vet, but it's generally considered safe for pregnant pets.
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Shumaila Saeed
Feb 06, 2024

Does Frontline Gold also kill ticks?

Yes, it's effective against ticks, including those that may transmit Lyme disease.
Shumaila Saeed
Shumaila Saeed
Feb 06, 2024

Should I switch from Frontline Plus to Gold?

Consider switching if you need faster or broader protection.
Shumaila Saeed
Shumaila Saeed
Feb 06, 2024

Can my pet swim after using Frontline Gold?

Yes, it's waterproof, but wait 24 hours before swimming or bathing.
Shumaila Saeed
Shumaila Saeed
Feb 06, 2024

Can Frontline Plus and Gold be used together?

No, there's no need to use them together.
Shumaila Saeed
Shumaila Saeed
Feb 06, 2024

Is Frontline Plus waterproof?

Yes, it's waterproof after 24 hours of application.
Shumaila Saeed
Shumaila Saeed
Feb 06, 2024

Where is Frontline Gold sold?

Like Frontline Plus, it's sold at vet clinics, pet stores, and online.
Shumaila Saeed
Shumaila Saeed
Feb 06, 2024

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About Author
Shumaila Saeed
Written by
Shumaila Saeed
Shumaila Saeed, an expert content creator with 6 years of experience, specializes in distilling complex topics into easily digestible comparisons, shining a light on the nuances that both inform and educate readers with clarity and accuracy.

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