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Antipsychotic vs. Antidepressant: Know the Difference

Shumaila Saeed
By Shumaila Saeed || Published on January 14, 2024
Antipsychotics are medications used to treat psychosis, including conditions like schizophrenia. Antidepressants are drugs prescribed to alleviate symptoms of depression and anxiety disorders.
Antipsychotic vs. Antidepressant

Key Differences

Antipsychotics are primarily used to manage psychosis, including hallucinations and delusions, often seen in schizophrenia and bipolar disorder. Antidepressants, in contrast, are designed to alleviate symptoms of depression, including persistent sadness and lack of interest in activities.
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Shumaila Saeed
Jan 14, 2024
The mechanism of action for antipsychotics typically involves dopamine receptor antagonism, which helps in reducing psychotic symptoms. Antidepressants, however, often work by altering the levels of neurotransmitters like serotonin and norepinephrine in the brain to improve mood and emotional state.
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Shumaila Saeed
Jan 14, 2024
Antipsychotic medications can also be used in the management of severe mood disorders and aggression. Antidepressants, besides treating depression, are also effective in treating a range of anxiety disorders, obsessive-compulsive disorder, and certain chronic pain conditions.
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Side effects of antipsychotics can include weight gain, drowsiness, and sometimes movement disorders. In contrast, antidepressants can cause side effects like sexual dysfunction, weight changes, and insomnia or drowsiness.
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Jan 14, 2024
Antipsychotics can be divided into two categories: typical and atypical, with the latter having fewer side effects. Antidepressants are categorized into several classes, including SSRIs, SNRIs, and tricyclics, each with different mechanisms and side effect profiles.
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Comparison Chart

Primary Use

Treating psychosis (e.g., schizophrenia, bipolar)
Treating depression and anxiety disorders
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Jan 14, 2024

Mechanism of Action

Dopamine receptor antagonism
Altering neurotransmitter levels (serotonin, etc.)
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Jan 14, 2024

Additional Uses

Managing severe mood disorders, aggression
Treating OCD, certain chronic pains
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Common Side Effects

Weight gain, drowsiness, movement disorders
Sexual dysfunction, weight changes, sleep issues
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Jan 14, 2024

Subcategories

Typical and atypical
SSRIs, SNRIs, tricyclics
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Antipsychotic and Antidepressant Definitions

Antipsychotic

Medication used in the treatment of schizophrenia.
The patient's schizophrenia was managed effectively with an antipsychotic.
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Dec 16, 2023

Antidepressant

Medication primarily used to treat major depressive disorder.
He started feeling better after taking an antidepressant for a few weeks.
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Shumaila Saeed
Dec 16, 2023

Antipsychotic

Medicines that can reduce aggression in certain mental health conditions.
An antipsychotic was used to calm the patient's aggressive outbursts.
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Dec 16, 2023

Antidepressant

Drugs that can increase serotonin levels in the brain.
Her doctor prescribed an antidepressant to balance her serotonin levels.
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Dec 16, 2023

Antipsychotic

A class of drugs for managing severe bipolar disorder.
Her bipolar episodes were better controlled when she was prescribed an antipsychotic.
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Dec 16, 2023
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Antidepressant

Medications that can be used for chronic pain management.
The doctor suggested an antidepressant for his chronic neuropathic pain.
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Antipsychotic

A drug that mitigates psychotic symptoms like delusions.
After starting the antipsychotic, his hallucinations significantly decreased.
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Dec 16, 2023

Antidepressant

Medicines often used for anxiety and panic disorders.
An antidepressant was effective in managing her panic attacks.
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Dec 16, 2023

Antipsychotic

Drugs that antagonize dopamine receptors in the brain.
The doctor explained that the antipsychotic works by blocking certain brain receptors.
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Dec 16, 2023

Antidepressant

A class of drugs that can improve mood and emotional well-being.
She felt her mood improve after the antidepressant regimen was initiated.
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Dec 16, 2023

Antipsychotic

Counteracting or diminishing the symptoms of psychotic disorders, such as schizophrenia.
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Dec 13, 2023

Antidepressant

A drug used to treat depression.
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Antipsychotic

An antipsychotic drug.
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Antidepressant

(pharmaceutical drug) An agent that prevents or counteracts depression.
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Dec 13, 2023

Antipsychotic

(pharmaceutical effect) Preventing or counteracting psychosis.
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Dec 13, 2023

Antidepressant

(pharmaceutical effect) Preventing or counteracting depression.
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Dec 13, 2023

Antipsychotic

(pharmaceutical drug) Any of a group of drugs used to treat psychosis.
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Dec 13, 2023

Antidepressant

Any of a class of drugs used to treat depression; often have undesirable side effects
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Antipsychotic

Tranquilizer used to treat psychotic conditions when a calming effect is desired
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Dec 13, 2023

Repeatedly Asked Queries

What are antipsychotics used for?

They are used to treat conditions like schizophrenia and bipolar disorder.
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Shumaila Saeed
Jan 14, 2024

What are the common side effects of antidepressants?

Common side effects may include nausea, insomnia, and sexual dysfunction.
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Jan 14, 2024

Are antidepressants safe during pregnancy?

The safety of antidepressants during pregnancy varies, and it's essential to discuss the risks and benefits with a healthcare provider if pregnant or planning to become pregnant.
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Jan 14, 2024

Can antidepressants be used for conditions other than depression and anxiety?

Sometimes, antidepressants are prescribed for other conditions like chronic pain, migraine, and certain eating disorders.
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Can antidepressants help with anxiety?

Yes, they are often prescribed for various anxiety disorders.
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Jan 14, 2024

Do antipsychotics have side effects?

Yes, they can cause weight gain, drowsiness, and sometimes movement disorders.
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Shumaila Saeed
Jan 14, 2024

Are antipsychotics only used for schizophrenia?

No, antipsychotics can also be prescribed for other conditions like bipolar disorder, schizoaffective disorder, and severe agitation.
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How long does it take for antidepressants to start working?

It can take several weeks for the full therapeutic effect of antidepressants to be felt, although some improvement may occur earlier.
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Jan 14, 2024

Are there different types of antidepressant medications?

Yes, there are several classes of antidepressants, including SSRIs, SNRIs, tricyclic antidepressants, and atypical antidepressants.
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Jan 14, 2024

Are there different types of antipsychotic medications?

Yes, antipsychotics are categorized into typical (first-generation) and atypical (second-generation) drugs, each with its own set of properties.
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Jan 14, 2024

Can you stop taking antidepressants suddenly?

It is generally not recommended to stop taking antidepressants abruptly, as it can lead to withdrawal symptoms. Tapering off under medical supervision is advised.
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Jan 14, 2024

How long does it take for antipsychotic medications to start working?

The onset of action can vary, but some improvement in symptoms may be seen within days to weeks, while the full effect may take several weeks to months.
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Are antidepressants effective for everyone with depression?

Antidepressant effectiveness can vary from person to person, and not all individuals with depression will respond equally to these medications. Different types may be tried if one is not effective.
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Jan 14, 2024

Can antipsychotics be used to treat anxiety or depression?

Occasionally, antipsychotics may be prescribed alongside other medications to help manage severe anxiety or depression, but they are not typically first-line treatments for these conditions.
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Shumaila Saeed
Jan 14, 2024

What is tardive dyskinesia, a side effect associated with some antipsychotics?

Tardive dyskinesia is a movement disorder characterized by involuntary, repetitive movements of the face and body, which can develop after long-term use of certain antipsychotic drugs.
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Shumaila Saeed
Jan 14, 2024

Is a prescription required for antipsychotic medication?

Yes, antipsychotic medications are prescription drugs and should be taken under medical supervision.
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Are antipsychotic medications addictive?

No, antipsychotics are not considered addictive.
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Jan 14, 2024

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About Author
Shumaila Saeed
Written by
Shumaila Saeed
Shumaila Saeed, an expert content creator with 6 years of experience, specializes in distilling complex topics into easily digestible comparisons, shining a light on the nuances that both inform and educate readers with clarity and accuracy.

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