Difference Between
versus

Prokaryotic Ribosomes vs. Eukaryotic Ribosomes: Know the Difference

Shumaila Saeed
By Shumaila Saeed || Updated on December 25, 2023
Prokaryotic ribosomes are smaller (70S) and simpler than eukaryotic ribosomes, which are larger (80S) and found in more complex cells.
Prokaryotic Ribosomes vs. Eukaryotic Ribosomes

Key Differences

Prokaryotic ribosomes are smaller, typically 70S in size, and are found in simpler, single-celled organisms without a nucleus. Eukaryotic ribosomes are larger, usually 80S, and are present in complex cells with a nucleus.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023
The 70S prokaryotic ribosome is made up of two subunits: 50S and 30S. The 80S eukaryotic ribosome comprises two different subunits: 60S and 40S.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023
Both prokaryotic and eukaryotic ribosomes play a crucial role in protein synthesis, but the process varies slightly due to differences in their RNA and protein content.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023
Many antibiotics selectively target prokaryotic ribosomes, disrupting their function without affecting eukaryotic ribosomes. This is due to structural differences between the two types.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023
In prokaryotes, ribosomes are distributed freely in the cytoplasm, while in eukaryotes, they are found both in the cytoplasm and on the rough endoplasmic reticulum.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023
ADVERTISEMENT

Comparison Chart

Size

Smaller (70S)
Larger (80S)
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

Subunit Composition

Made up of 50S and 30S subunits
Comprises 60S and 40S subunits
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

Function in Protein Synthesis

Similar role, but with slight process variations
Similar role, adapted to more complex cell machinery
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

Sensitivity to Antibiotics

Generally more sensitive
Less sensitive
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

Cellular Location

Freely in the cytoplasm
In cytoplasm and on rough ER
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023
ADVERTISEMENT

Prokaryotic Ribosomes and Eukaryotic Ribosomes Definitions

Prokaryotic Ribosomes

Comprise 50S and 30S subunits.
The 50S and 30S subunits assemble to form prokaryotic ribosomes.
Shumaila Saeed
Shumaila Saeed
Dec 03, 2023

Eukaryotic Ribosomes

Comprise 60S and 40S subunits.
The 60S and 40S subunits join together to form eukaryotic ribosomes.
Shumaila Saeed
Shumaila Saeed
Dec 03, 2023

Prokaryotic Ribosomes

More sensitive to antibiotics than eukaryotic ribosomes.
Antibiotics like tetracycline inhibit prokaryotic ribosomes.
Shumaila Saeed
Shumaila Saeed
Dec 03, 2023

Eukaryotic Ribosomes

Less sensitive to antibiotics than prokaryotic ribosomes.
Most antibiotics do not affect eukaryotic ribosomes.
Shumaila Saeed
Shumaila Saeed
Dec 03, 2023

Prokaryotic Ribosomes

Essential for protein synthesis in bacteria.
Prokaryotic ribosomes are crucial for bacterial growth and reproduction.
Shumaila Saeed
Shumaila Saeed
Dec 03, 2023
ADVERTISEMENT

Eukaryotic Ribosomes

Larger ribosomes (80S) in eukaryotic cells.
Eukaryotic ribosomes are integral to protein production in human cells.
Shumaila Saeed
Shumaila Saeed
Dec 03, 2023

Prokaryotic Ribosomes

Found freely floating in the cytoplasm.
In bacteria, prokaryotic ribosomes synthesize proteins in the cytoplasm.
Shumaila Saeed
Shumaila Saeed
Dec 03, 2023

Eukaryotic Ribosomes

Involved in protein synthesis in complex cells.
Eukaryotic ribosomes are found in both animal and plant cells.
Shumaila Saeed
Shumaila Saeed
Dec 03, 2023

Prokaryotic Ribosomes

Smaller ribosomes (70S) in prokaryotic cells.
Prokaryotic ribosomes are targets for certain antibiotics.
Shumaila Saeed
Shumaila Saeed
Dec 03, 2023

Eukaryotic Ribosomes

Located in the cytoplasm and on the rough endoplasmic reticulum.
Eukaryotic ribosomes on the rough ER synthesize membrane-bound proteins.
Shumaila Saeed
Shumaila Saeed
Dec 03, 2023

Repeatedly Asked Queries

What are eukaryotic ribosomes?

They are larger ribosomes found in more complex eukaryotic cells.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

What size are eukaryotic ribosomes?

They are usually 80S in size.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

What makes prokaryotic ribosomes different from eukaryotic ones?

They differ in size, sensitivity to antibiotics, and cellular location.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

Where are eukaryotic ribosomes found?

In the cytoplasm and on the rough endoplasmic reticulum.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

What are the subunits of eukaryotic ribosomes?

They comprise 60S and 40S subunits.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

What are prokaryotic ribosomes?

They are smaller ribosomes found in prokaryotic cells, like bacteria.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

What size are prokaryotic ribosomes?

They are typically 70S in size.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

Are prokaryotic ribosomes simpler than eukaryotic ones?

Yes, they are generally considered simpler.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

Can prokaryotic ribosomes be inhibited by drugs?

Yes, many antibiotics inhibit prokaryotic ribosomes.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

Is the function of prokaryotic ribosomes different from eukaryotic ribosomes?

The basic function of protein synthesis is similar, but the process varies slightly.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

Can antibiotics target eukaryotic ribosomes?

Generally, no. Antibiotics usually target prokaryotic ribosomes.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

Where are prokaryotic ribosomes located in the cell?

They are found freely floating in the cytoplasm.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

Do prokaryotic and eukaryotic ribosomes have different RNA content?

Yes, there are differences in their RNA and protein compositions.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

Are prokaryotic ribosomes involved in protein synthesis?

Yes, they play a key role in protein synthesis in prokaryotic cells.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

Do eukaryotic ribosomes synthesize proteins?

Yes, they are essential for protein synthesis in eukaryotic cells.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

Do eukaryotic ribosomes have a more complex structure?

Yes, they are more complex and larger in size.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

Are eukaryotic ribosomes affected by common antibiotics?

Generally, no, they are less sensitive to antibiotics.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

Why are eukaryotic ribosomes not targeted by most antibiotics?

Because of their structural differences from prokaryotic ribosomes.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

Can the differences in ribosomes be used for medical treatments?

Yes, targeting prokaryotic ribosomes is a basis for many antibiotic therapies.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

What are the subunits of prokaryotic ribosomes?

They consist of 50S and 30S subunits.
Shumaila Saeed
Shumaila Saeed
Dec 10, 2023

Share this page

Link for your blog / website
HTML
Link to share via messenger
About Author
Shumaila Saeed
Written by
Shumaila Saeed
Shumaila Saeed, an expert content creator with 6 years of experience, specializes in distilling complex topics into easily digestible comparisons, shining a light on the nuances that both inform and educate readers with clarity and accuracy.

Popular Comparisons

Trending Comparisons

FPTP vs. PRFPTP vs. PR
Shumaila SaeedShumaila Saeed
February 16, 2024
FPTP (First Past the Post) is a simple plurality voting system where the candidate with most votes wins; PR (Proportional Representation) allocates seats based on the proportion of votes each party receives.
Japanese Eyes vs. Chinese EyesJapanese Eyes vs. Chinese Eyes
Shumaila SaeedShumaila Saeed
December 25, 2023
Japanese Eyes and Chinese Eyes refer to linguistic structures in Japanese and Chinese respectively, each reflecting unique aspects of grammar and syntax.
Pulley vs. SheavePulley vs. Sheave
Hifza NasirHifza Nasir
April 4, 2024
A pulley is a wheel on an axle designed to support movement and change of direction of a taut cable, while a sheave is the wheel part of a pulley system that specifically interacts with the cable.
2 Pole Motors vs. 4 Pole Motors2 Pole Motors vs. 4 Pole Motors
Shumaila SaeedShumaila Saeed
December 25, 2023
2 Pole Motors have one pair of magnetic poles and run at higher speeds, while 4 Pole Motors have two pairs of poles and operate at lower speeds, offering higher torque.
Extent vs. ScopeExtent vs. Scope
Shumaila SaeedShumaila Saeed
December 25, 2023
"Extent" refers to the degree or range something covers, while "Scope" relates to the breadth or range of coverage, influence, or effect.
Poem vs. PoetryPoem vs. Poetry
Shumaila SaeedShumaila Saeed
December 25, 2023
A poem is a piece of writing that expresses ideas and emotions with a distinctive style and rhythm; poetry is the art form of writing such pieces.
Login vs. LogonLogin vs. Logon
Shumaila SaeedShumaila Saeed
December 25, 2023
"Login" and "Logon" are often used interchangeably to describe the process of gaining access to a computer system, but "login" can also refer to the credentials used for access.
Nuclear Family vs. Joint FamilyNuclear Family vs. Joint Family
Shumaila SaeedShumaila Saeed
January 9, 2024
Nuclear Family is a family unit consisting of parents and their children. Joint Family is a larger family structure comprising parents, children, and other relatives living together.
Poster vs. InfographicPoster vs. Infographic
Shumaila SaeedShumaila Saeed
December 25, 2023
A Poster is a large printed image or notice for public display, while an Infographic is a visual representation of information or data.
NM3 vs. M3NM3 vs. M3
Hifza NasirHifza Nasir
April 19, 2024
NM3 measures gas volume under Normal conditions (0°C and 1.01325 bar), while M3 measures volume under the conditions at which it is measured, without standard adjustment.
Vital Proteins Collagen vs. OrganikaVital Proteins Collagen vs. Organika
Shumaila SaeedShumaila Saeed
February 9, 2024
Vital Proteins Collagen is a brand offering collagen supplements for health and beauty, while Organika is a broader health and wellness brand with diverse products including collagen.
Data Roaming vs. Cellular DataData Roaming vs. Cellular Data
Shumaila SaeedShumaila Saeed
December 25, 2023
Data Roaming allows usage of mobile network services outside of the home network area, while Cellular Data is using mobile services within the home network.
Slazenger Logo vs. Puma LogoSlazenger Logo vs. Puma Logo
Shumaila SaeedShumaila Saeed
February 15, 2024
The Slazenger logo features a panther, symbolizing agility and tradition, while the Puma logo depicts a leaping puma, representing speed and strength.
Catapult vs. TrebuchetCatapult vs. Trebuchet
Shumaila SaeedShumaila Saeed
January 4, 2024
A catapult is a ballistic device using tension or torsion to launch projectiles, while a trebuchet is a type of catapult using a counterweight for greater force and distance.
Pycharm Community vs. Pycharm ProPycharm Community vs. Pycharm Pro
Shumaila SaeedShumaila Saeed
February 4, 2024
PyCharm Community is a free, open-source IDE for Python development, while PyCharm Pro is a paid version with additional advanced features like web development support and database tools.
Fluid vs. LiquidFluid vs. Liquid
Shumaila SaeedShumaila Saeed
February 13, 2024
Fluids encompass all substances that flow (including gases and liquids), while liquids specifically refer to fluids with a definite volume but no fixed shape, adapting to their container.
Gorilla Glass 3 vs. Gorilla Glass 5Gorilla Glass 3 vs. Gorilla Glass 5
Shumaila SaeedShumaila Saeed
January 1, 2024
Gorilla Glass 3 offers improved scratch resistance and durability compared to its predecessors, while Gorilla Glass 5 focuses on enhanced drop protection and toughness.
5'11" vs. 6'0"5’11” vs. 6’0″
Shumaila SaeedShumaila Saeed
February 4, 2024
The difference between 5'11" and 6'0" is one inch, with 5'11" being 71 inches and 6'0" being 72 inches tall.
DDR3 vs. DDR3LDDR3 vs. DDR3L
Shumaila SaeedShumaila Saeed
January 29, 2024
DDR3 is a type of RAM with standard voltage (1.5V), while DDR3L is a low voltage variant (1.35V) compatible with both 1.5V and 1.35V slots.
PPM vs. PPMVPPM vs. PPMV
Shumaila SaeedShumaila Saeed
February 10, 2024
PPM (parts per million) measures the concentration of one substance within a million parts of another. PPMV (parts per million by volume) expresses gas concentration as volume per million volumes of air.
NDM vs. FTPNDM vs. FTP
Shumaila SaeedShumaila Saeed
February 15, 2024
NDM (Network Data Mover) automates and secures data transfers across networks, while FTP (File Transfer Protocol) is a standard network protocol for transferring files between computers.
Traditional Trade vs. Modern TradeTraditional Trade vs. Modern Trade
Shumaila SaeedShumaila Saeed
December 25, 2023
Traditional trade involves local, small-scale, often personalized commerce; modern trade is characterized by large-scale, technology-driven, and impersonal retail environments.
Crane vs. HeronCrane vs. Heron
Shumaila SaeedShumaila Saeed
June 24, 2024
Cranes are large, long-legged and long-necked birds known for their elaborate dances, while herons are typically more solitary, stealth hunters with a distinctive S-shaped neck.
Explain vs. DefineExplain vs. Define
Dua FatimaDua Fatima
June 22, 2024
Explaining involves detailing or clarifying a concept, often including context and examples, whereas defining means stating the exact meaning of a word or phrase, typically in a concise manner.

Featured Comparisons

New Comparisons