Difference Between
versus

Paxil vs. Zoloft: Know the Difference

Shumaila Saeed
By Shumaila Saeed || Published on February 20, 2024
Paxil is an antidepressant medication, used primarily to treat depression and anxiety disorders; Zoloft is also an antidepressant, commonly used for depression and anxiety but differs in its specific chemical makeup and side effects.
Paxil vs. Zoloft

Key Differences

Paxil, known generically as paroxetine, is a selective serotonin reuptake inhibitor (SSRI) primarily used for treating depression, anxiety disorders, and post-traumatic stress disorder. Zoloft, with the generic name sertraline, is another SSRI but is often prescribed for additional conditions like obsessive-compulsive disorder and premenstrual dysphoric disorder.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024
The side effects of Paxil can include sexual dysfunction, weight gain, and withdrawal symptoms upon discontinuation. In contrast, Zoloft tends to have a lower risk of sexual side effects and may be a preferred option for individuals concerned about these issues.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024
Paxil is known for its sedative properties, which can be beneficial for patients with anxiety disorders who require a calming medication. Zoloft, on the other hand, is less sedating and might be a better choice for individuals who need to maintain alertness and energy levels.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024
Paxil has a shorter half-life, meaning it leaves the body quicker, which can result in more pronounced withdrawal symptoms if not tapered properly. Zoloft has a longer half-life, offering a potentially smoother transition when discontinuing or changing medications.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024
While both Paxil and Zoloft are effective for depression and anxiety, Paxil is often prescribed for older adults due to its effectiveness in treating late-life depression. Zoloft is frequently chosen for younger patients, especially those who may also suffer from panic attacks.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024
ADVERTISEMENT

Comparison Chart

Generic Name

Paroxetine
Sertraline
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

Primary Use

Depression, Anxiety, PTSD
Depression, Anxiety, OCD, PMDD
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

Side Effects

Sexual dysfunction, Weight gain
Lower risk of sexual side effects
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

Sedation Level

More sedating
Less sedating
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

Half-Life

Shorter
Longer
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024
ADVERTISEMENT

Paxil and Zoloft Definitions

Paxil

An antidepressant medication.
The doctor prescribed Paxil for her depression.
Shumaila Saeed
Shumaila Saeed
Jan 16, 2024

Zoloft

Used for obsessive-compulsive disorder treatment.
Her OCD improved after starting Zoloft therapy.
Shumaila Saeed
Shumaila Saeed
Jan 16, 2024

Paxil

A medication effective in treating post-traumatic stress disorder.
Paxil helped her cope with the symptoms of PTSD.
Shumaila Saeed
Shumaila Saeed
Jan 16, 2024

Zoloft

A medication for treating anxiety disorders.
Zoloft was effective in reducing his anxiety symptoms.
Shumaila Saeed
Shumaila Saeed
Jan 16, 2024

Paxil

A drug used to treat anxiety disorders.
After starting Paxil, his anxiety symptoms improved significantly.
Shumaila Saeed
Shumaila Saeed
Jan 16, 2024
ADVERTISEMENT

Zoloft

An antidepressant primarily used for depression.**
She began taking Zoloft to help with her depression.
Shumaila Saeed
Shumaila Saeed
Jan 16, 2024

Paxil

A selective serotonin reuptake inhibitor.
Paxil works by increasing serotonin levels in the brain.
Shumaila Saeed
Shumaila Saeed
Jan 16, 2024

Zoloft

A selective serotonin reuptake inhibitor like Paxil.
Zoloft, an SSRI, was chosen for its fewer side effects.
Shumaila Saeed
Shumaila Saeed
Jan 16, 2024

Paxil

Used for treating social anxiety disorder.
His social anxiety disorder was managed well with Paxil.
Shumaila Saeed
Shumaila Saeed
Jan 16, 2024

Zoloft

Prescribed for premenstrual dysphoric disorder.
Zoloft helped alleviate her symptoms of PMDD.
Shumaila Saeed
Shumaila Saeed
Jan 16, 2024

Paxil

A selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade name Paxil)
Shumaila Saeed
Shumaila Saeed
Jan 16, 2024

Zoloft

A selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade name Zoloft)
Shumaila Saeed
Shumaila Saeed
Jan 16, 2024

Repeatedly Asked Queries

What is Paxil used for?

Paxil is primarily used for treating depression and various anxiety disorders.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

Can Paxil cause weight gain?

Yes, weight gain can be a side effect of Paxil.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

Is Zoloft less likely to cause sexual side effects?

Zoloft tends to have a lower risk of sexual side effects compared to Paxil.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

Can Paxil treat PTSD?

Yes, Paxil is effective in treating PTSD.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

Are Paxil and Zoloft similar?

Both are SSRIs, but they have different side effect profiles and specific uses.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

What conditions is Zoloft prescribed for?

Zoloft is prescribed for depression, anxiety, OCD, and PMDD.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

Are there withdrawal symptoms with Paxil?

Paxil can have pronounced withdrawal symptoms if not tapered properly.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

Can Zoloft be used for panic attacks?

Yes, Zoloft is effective for treating panic attacks.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

Is Paxil sedating?

Paxil has sedative properties, making it beneficial for anxiety disorders.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

Can Zoloft cause withdrawal symptoms?

While Zoloft can cause withdrawal symptoms, they are generally milder due to its longer half-life.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

Is Zoloft used for OCD?

Yes, Zoloft is often prescribed for obsessive-compulsive disorder.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

Is Zoloft better for younger patients?

Zoloft is often preferred for younger patients, especially those with panic disorders.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

Why might Paxil be prescribed for older adults?

Paxil is effective in treating late-life depression, making it a common choice for older adults.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

Does Zoloft have a longer half-life than Paxil?

Yes, Zoloft has a longer half-life, which affects withdrawal symptoms.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

Does Zoloft treat premenstrual dysphoric disorder?

Yes, Zoloft is used to treat PMDD.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

What is the generic name of Zoloft?

The generic name for Zoloft is sertraline.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

Is Paxil good for social anxiety?

Paxil is often prescribed for social anxiety disorder.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

Can Paxil cause sexual dysfunction?

Yes, sexual dysfunction is a possible side effect of Paxil.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

How do Paxil and Zoloft affect serotonin?

Both Paxil and Zoloft increase serotonin levels in the brain, helping to alleviate symptoms of depression and anxiety.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

What is the generic name of Paxil?

The generic name for Paxil is paroxetine.
Shumaila Saeed
Shumaila Saeed
Feb 20, 2024

Share this page

Link for your blog / website
HTML
Link to share via messenger
About Author
Shumaila Saeed
Written by
Shumaila Saeed
Shumaila Saeed, an expert content creator with 6 years of experience, specializes in distilling complex topics into easily digestible comparisons, shining a light on the nuances that both inform and educate readers with clarity and accuracy.

Popular Comparisons

Trending Comparisons

FPTP vs. PRFPTP vs. PR
Shumaila SaeedShumaila Saeed
February 16, 2024
FPTP (First Past the Post) is a simple plurality voting system where the candidate with most votes wins; PR (Proportional Representation) allocates seats based on the proportion of votes each party receives.
Japanese Eyes vs. Chinese EyesJapanese Eyes vs. Chinese Eyes
Shumaila SaeedShumaila Saeed
December 25, 2023
Japanese Eyes and Chinese Eyes refer to linguistic structures in Japanese and Chinese respectively, each reflecting unique aspects of grammar and syntax.
2 Pole Motors vs. 4 Pole Motors2 Pole Motors vs. 4 Pole Motors
Shumaila SaeedShumaila Saeed
December 25, 2023
2 Pole Motors have one pair of magnetic poles and run at higher speeds, while 4 Pole Motors have two pairs of poles and operate at lower speeds, offering higher torque.
Login vs. LogonLogin vs. Logon
Shumaila SaeedShumaila Saeed
December 25, 2023
"Login" and "Logon" are often used interchangeably to describe the process of gaining access to a computer system, but "login" can also refer to the credentials used for access.
Extent vs. ScopeExtent vs. Scope
Shumaila SaeedShumaila Saeed
December 25, 2023
"Extent" refers to the degree or range something covers, while "Scope" relates to the breadth or range of coverage, influence, or effect.
Poem vs. PoetryPoem vs. Poetry
Shumaila SaeedShumaila Saeed
December 25, 2023
A poem is a piece of writing that expresses ideas and emotions with a distinctive style and rhythm; poetry is the art form of writing such pieces.
Pulley vs. SheavePulley vs. Sheave
Hifza NasirHifza Nasir
April 4, 2024
A pulley is a wheel on an axle designed to support movement and change of direction of a taut cable, while a sheave is the wheel part of a pulley system that specifically interacts with the cable.
Nuclear Family vs. Joint FamilyNuclear Family vs. Joint Family
Shumaila SaeedShumaila Saeed
January 9, 2024
Nuclear Family is a family unit consisting of parents and their children. Joint Family is a larger family structure comprising parents, children, and other relatives living together.
NM3 vs. M3NM3 vs. M3
Hifza NasirHifza Nasir
April 19, 2024
NM3 measures gas volume under Normal conditions (0°C and 1.01325 bar), while M3 measures volume under the conditions at which it is measured, without standard adjustment.
Slazenger Logo vs. Puma LogoSlazenger Logo vs. Puma Logo
Shumaila SaeedShumaila Saeed
February 15, 2024
The Slazenger logo features a panther, symbolizing agility and tradition, while the Puma logo depicts a leaping puma, representing speed and strength.
Catapult vs. TrebuchetCatapult vs. Trebuchet
Shumaila SaeedShumaila Saeed
January 4, 2024
A catapult is a ballistic device using tension or torsion to launch projectiles, while a trebuchet is a type of catapult using a counterweight for greater force and distance.
Vital Proteins Collagen vs. OrganikaVital Proteins Collagen vs. Organika
Shumaila SaeedShumaila Saeed
February 9, 2024
Vital Proteins Collagen is a brand offering collagen supplements for health and beauty, while Organika is a broader health and wellness brand with diverse products including collagen.
5'11" vs. 6'0"5’11” vs. 6’0″
Shumaila SaeedShumaila Saeed
February 4, 2024
The difference between 5'11" and 6'0" is one inch, with 5'11" being 71 inches and 6'0" being 72 inches tall.
Data Roaming vs. Cellular DataData Roaming vs. Cellular Data
Shumaila SaeedShumaila Saeed
December 25, 2023
Data Roaming allows usage of mobile network services outside of the home network area, while Cellular Data is using mobile services within the home network.
4D Battery vs. 8D Battery4D Battery vs. 8D Battery
Shumaila SaeedShumaila Saeed
February 7, 2024
4D batteries are smaller, heavy-duty batteries used in commercial applications, whereas 8D batteries are larger, providing more power and capacity for large vehicles and machinery.
Gorilla Glass 3 vs. Gorilla Glass 5Gorilla Glass 3 vs. Gorilla Glass 5
Shumaila SaeedShumaila Saeed
January 1, 2024
Gorilla Glass 3 offers improved scratch resistance and durability compared to its predecessors, while Gorilla Glass 5 focuses on enhanced drop protection and toughness.
DDR3 vs. DDR3LDDR3 vs. DDR3L
Shumaila SaeedShumaila Saeed
January 29, 2024
DDR3 is a type of RAM with standard voltage (1.5V), while DDR3L is a low voltage variant (1.35V) compatible with both 1.5V and 1.35V slots.
Pycharm Community vs. Pycharm ProPycharm Community vs. Pycharm Pro
Shumaila SaeedShumaila Saeed
February 4, 2024
PyCharm Community is a free, open-source IDE for Python development, while PyCharm Pro is a paid version with additional advanced features like web development support and database tools.
Crane vs. HeronCrane vs. Heron
Shumaila SaeedShumaila Saeed
June 24, 2024
Cranes are large, long-legged and long-necked birds known for their elaborate dances, while herons are typically more solitary, stealth hunters with a distinctive S-shaped neck.
Traditional Trade vs. Modern TradeTraditional Trade vs. Modern Trade
Shumaila SaeedShumaila Saeed
December 25, 2023
Traditional trade involves local, small-scale, often personalized commerce; modern trade is characterized by large-scale, technology-driven, and impersonal retail environments.
NDM vs. FTPNDM vs. FTP
Shumaila SaeedShumaila Saeed
February 15, 2024
NDM (Network Data Mover) automates and secures data transfers across networks, while FTP (File Transfer Protocol) is a standard network protocol for transferring files between computers.
Fluid vs. LiquidFluid vs. Liquid
Shumaila SaeedShumaila Saeed
February 13, 2024
Fluids encompass all substances that flow (including gases and liquids), while liquids specifically refer to fluids with a definite volume but no fixed shape, adapting to their container.
Explain vs. DefineExplain vs. Define
Dua FatimaDua Fatima
June 22, 2024
Explaining involves detailing or clarifying a concept, often including context and examples, whereas defining means stating the exact meaning of a word or phrase, typically in a concise manner.
Char vs. VarcharChar vs. Varchar
Dua FatimaDua Fatima
June 23, 2024
Char stores fixed-length strings; efficient for known sizes. Varchar stores variable-length strings, saving space for shorter inputs.

Featured Comparisons

New Comparisons