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Myeloblast vs. Lymphoblast: Know the Difference

Shumaila Saeed
By Shumaila Saeed || Published on February 24, 2024
Myeloblasts are precursors to granulocytes in the bone marrow, while lymphoblasts are precursors to lymphocytes, key in adaptive immunity.
Myeloblast vs. Lymphoblast

Key Differences

Myeloblasts are immature cells in the bone marrow, developing into granulocytes (neutrophils, eosinophils, basophils). Lymphoblasts, also originating in the bone marrow, differentiate into lymphocytes, crucial for immune responses.
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Shumaila Saeed
Feb 24, 2024
In the development of the immune system, myeloblasts are part of the myeloid lineage, contributing to innate immunity. Lymphoblasts are part of the lymphoid lineage, evolving into cells vital for adaptive immunity (B cells, T cells).
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Shumaila Saeed
Feb 24, 2024
Myeloblasts, when abnormally proliferated, are associated with certain types of leukemia, specifically acute myeloid leukemia (AML). Lymphoblasts, when they proliferate excessively, lead to acute lymphoblastic leukemia (ALL).
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Feb 24, 2024
Morphologically, myeloblasts are characterized by a large nucleus and a small amount of cytoplasm. Lymphoblasts are similar but can be distinguished by their specific surface markers and slightly different nuclear morphology.
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Shumaila Saeed
Feb 24, 2024
In clinical pathology, myeloblasts are identified and quantified for diagnosing and monitoring myeloid disorders. Lymphoblasts are analyzed in the context of lymphoid disorders and certain types of leukemia.
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Comparison Chart

Cell Lineage

Myeloid lineage
Lymphoid lineage
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Development Into

Granulocytes (neutrophils, eosinophils, basophils)
Lymphocytes (B cells, T cells)
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Role in Immunity

Part of innate immune system
Key in adaptive immune system
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Leukemia Association

Associated with acute myeloid leukemia (AML)
Associated with acute lymphoblastic leukemia (ALL)
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Morphology

Large nucleus, small cytoplasm
Similar size but distinct surface markers and nuclear morphology
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Myeloblast and Lymphoblast Definitions

Myeloblast

Myeloblasts are immature blood cells in the bone marrow, precursor to granulocytes.
The increased number of myeloblasts indicated a possible case of AML.
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Shumaila Saeed
Jan 17, 2024

Lymphoblast

Lymphoblasts have distinct markers differentiating them from other blood cells.
The lab tests focused on identifying the unique characteristics of lymphoblasts.
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Jan 17, 2024

Myeloblast

Myeloblasts are early cells in the myeloid cell line, crucial for innate immunity.
Myeloblasts differentiate into various types of granulocytes.
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Jan 17, 2024

Lymphoblast

Lymphoblasts, when proliferated abnormally, are linked to acute lymphoblastic leukemia.
Her diagnosis was based on the abnormal increase of lymphoblasts.
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Myeloblast

Myeloblasts are essential in the production of white blood cells in the myeloid line.
The treatment aimed to regulate the production of myeloblasts in her marrow.
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Lymphoblast

Lymphoblasts are immature cells that develop into lymphocytes in the immune system.
The lymphoblasts in his sample were examined for signs of ALL.
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Myeloblast

Myeloblasts are a type of hematopoietic cell, involved in blood cell formation.
The maturation of myeloblasts into neutrophils is vital for infection response.
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Jan 17, 2024

Lymphoblast

Lymphoblasts originate from the lymphoid cell line, differentiating into B and T cells.
Lymphoblasts are critical for adaptive immunity, evolving into specialized lymphocytes.
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Jan 17, 2024

Myeloblast

Myeloblasts, identified by their large nucleus, are indicative of certain blood disorders.
In his bone marrow biopsy, the pathologist noted an abundance of myeloblasts.
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Lymphoblast

Lymphoblasts are key players in the body's defense against infections and diseases.
The effectiveness of vaccines depends partly on the response of lymphoblasts.
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Myeloblast

An immature cell of the bone marrow that is the precursor of a myelocyte.
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Lymphoblast

A large, immature lymphocyte that has been activated by an antigen and divides to give rise to mature lymphocytes (B cells and T cells).
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Myeloblast

(biology) An immature cell of bone marrow that develops into a myelocyte.
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Lymphoblast

An immature lymphocyte; they proliferate uncontrollably in lymphoblastic leukemia
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Myeloblast

A precursor of leukocytes that normally occurs only in bone marrow
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Lymphoblast

An immature lymphocyte
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Repeatedly Asked Queries

What diseases are associated with abnormal myeloblasts?

Abnormal proliferation of myeloblasts is associated with acute myeloid leukemia (AML).
Shumaila Saeed
Shumaila Saeed
Feb 24, 2024

Are myeloblasts part of the adaptive immune system?

No, myeloblasts are part of the innate immune system.
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Shumaila Saeed
Feb 24, 2024

What conditions are linked to abnormal lymphoblasts?

Abnormal lymphoblasts are often linked to acute lymphoblastic leukemia (ALL).
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Shumaila Saeed
Feb 24, 2024

How are myeloblasts identified in the lab?

Myeloblasts are identified by their large nucleus and small amount of cytoplasm.
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Shumaila Saeed
Feb 24, 2024

What are the identifying features of lymphoblasts?

Lymphoblasts are identified by specific surface markers and nuclear morphology.
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What is the function of lymphoblasts?

Lymphoblasts are important for generating lymphocytes, vital for adaptive immunity.
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Can myeloblasts develop into lymphocytes?

No, myeloblasts develop into granulocytes, not lymphocytes.
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Can myeloblasts be found in peripheral blood?

Myeloblasts are usually confined to the bone marrow and not typically found in peripheral blood.
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What is a myeloblast?

A myeloblast is an immature blood cell in the bone marrow, developing into granulocytes.
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Shumaila Saeed
Feb 24, 2024

What is a lymphoblast?

A lymphoblast is an immature cell that differentiates into lymphocytes in the immune system.
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Do lymphoblasts contribute to innate immunity?

Lymphoblasts primarily contribute to the adaptive immune system.
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Do lymphoblasts turn into granulocytes?

No, lymphoblasts differentiate into lymphocytes.
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What stimulates lymphoblast development?

Lymphoblast development is stimulated by immune challenges, aiding in adaptive immune responses.
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What triggers the production of myeloblasts?

Myeloblast production is triggered by the body's need for more granulocytes, often in response to infection.
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What role do myeloblasts play in the body?

Myeloblasts are crucial for producing granulocytes, key in the innate immune response.
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Are lymphoblasts present in normal blood?

Lymphoblasts are normally present in the bone marrow, not in circulating blood.
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What is the lifespan of a myeloblast?

Myeloblasts have a short lifespan, quickly maturing into mature granulocytes.
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How long do lymphoblasts live?

Lymphoblasts also have a relatively short lifespan before they mature into lymphocytes.
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Are myeloblasts involved in allergic reactions?

Yes, myeloblasts can develop into eosinophils, which are involved in allergic responses.
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Do lymphoblasts have a role in allergies?

Lymphoblasts primarily function in adaptive immunity and are less directly involved in typical allergic reactions.
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About Author
Shumaila Saeed
Written by
Shumaila Saeed
Shumaila Saeed, an expert content creator with 6 years of experience, specializes in distilling complex topics into easily digestible comparisons, shining a light on the nuances that both inform and educate readers with clarity and accuracy.

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