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Chloroform vs. Dichloromethane: Know the Difference

Shumaila Saeed
By Shumaila Saeed || Published on January 27, 2024
Chloroform, a dense, sweet-smelling liquid, was historically used as an anesthetic, while Dichloromethane, a colorless, volatile liquid, is primarily used as a solvent.
Chloroform vs. Dichloromethane

Key Differences

Chloroform, known chemically as trichloromethane, has been historically used as an anesthetic due to its sedative properties. Dichloromethane (DCM), however, is mainly used as a solvent in various industries due to its ability to dissolve a wide range of compounds.
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Jan 27, 2024
While Chloroform contains three chlorine atoms attached to a methane molecule, Dichloromethane has only two chlorine atoms, altering their chemical properties and uses.
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Chloroform is heavier and less volatile compared to Dichloromethane, making it less ideal for applications requiring quick evaporation.
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The use of Chloroform has decreased due to its potential health hazards and carcinogenic properties, whereas Dichloromethane is still widely used, though with safety precautions due to its toxicity and potential carcinogenic effects.
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In terms of environmental impact, Chloroform is more regulated due to its harmful effects, whereas Dichloromethane, although regulated, is more commonly found in industrial applications.
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Comparison Chart

Chemical Composition

Trichloromethane (CHCl3)
Dichloromethane (CH2Cl2)
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Primary Use

Historically used as an anesthetic
Widely used as a solvent
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Volatility

Less volatile
More volatile
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Health Hazards

Potentially carcinogenic, less used due to health concerns
Toxic, used with safety measures
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Environmental Impact

More regulated due to harmful effects
Still widely used but regulated
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Chloroform and Dichloromethane Definitions

Chloroform

A dense, sweet-smelling liquid, now mostly used in laboratories.
The laboratory stored chloroform for experimental purposes.
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Dichloromethane

Dichloromethane is colorless and possesses a sweet aroma.
The colorless liquid in the bottle was identified as dichloromethane.
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Chloroform

Occasionally used in fire extinguishers.
Some fire extinguishers contain chloroform for specific fire types.
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Dichloromethane

Used in the production of pharmaceuticals.
Dichloromethane plays a role in synthesizing certain medications.
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Chloroform

Used in the past in refrigeration applications.
Chloroform was an ingredient in older refrigeration systems.
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Dichloromethane

Considered a less harmful alternative to chloroform in some applications.
Dichloromethane is used as a safer alternative to chloroform.
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Chloroform

A clear, colorless, dense, sweet-smelling liquid, CHCl3, used in refrigerants, propellants, and resins, as a solvent, and sometimes as an anesthetic. Chloroform, once widely used in human and veterinary surgery, has generally been replaced by less toxic, more easily controlled agents.
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Dichloromethane

A volatile organic compound used as a solvent.
Dichloromethane is often used to dissolve various chemicals.
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Chloroform

To treat with chloroform to anesthetize, render unconscious, or kill.
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Dichloromethane

It's used in paint removers and degreasers.
He used a dichloromethane-based solution to remove paint.
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Chloroform

To apply chloroform to.
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Dichloromethane

(organic compound) The partially halogenated hydrocarbon CH2Cl2 widely used as a solvent
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Chloroform

(organic compound) A halogenated hydrocarbon, trichloromethane, CHCl3; it is a volatile, sweet-smelling liquid, used extensively as a solvent and formerly as an anesthetic.
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Dichloromethane

A nonflammable liquid used as a solvent and paint remover and refrigerant
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Chloroform

To treat with chloroform, or to render unconscious with chloroform.
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Chloroform

A colorless volatile liquid, CHCl3, having an ethereal odor and a sweetish taste, formed by treating alcohol with chlorine and an alkali. It is a powerful solvent of wax, resin, etc., and is extensively used to produce anæsthesia in surgical operations; also externally, to alleviate pain.
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Chloroform

To treat with chloroform, or to place under its influence.
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Chloroform

A volatile liquid haloform (CHCl3); formerly used as an anesthetic;
Chloroform was the first inhalation anesthetic
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Chloroform

Anesthetize with chloroform;
Doctors used to put people under by chloroforming them
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Chloroform

An organic compound historically used as an anesthetic.
Chloroform was once a common anesthetic in surgeries.
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Chloroform

Chloroform has potential carcinogenic and health risks.
Due to its risks, chloroform usage is now limited.
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Repeatedly Asked Queries

What are the health risks of Chloroform?

It's potentially carcinogenic and can cause liver and kidney damage.
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Can Dichloromethane dissolve plastics?

Yes, it can dissolve certain types of plastics.
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Is Dichloromethane heavier than water?

Yes, it's denser than water.
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Was Chloroform used in firefighting?

Yes, in some types of fire extinguishers.
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Can Dichloromethane be used in food processing?

No, it's not safe for food processing.
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How is Chloroform disposed of?

It must be disposed of as hazardous waste.
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Is Chloroform still used in medical procedures?

No, it's rarely used due to safety concerns.
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Is Dichloromethane found in household products?

Yes, it's in some paint removers and degreasers.
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Can Chloroform be found naturally?

Yes, in small amounts in certain environments.
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Can Chloroform cause unconsciousness?

Yes, it can induce unconsciousness.
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How is Dichloromethane produced?

Mainly through the chlorination of methane.
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Was Chloroform used in refrigerants?

Yes, in older refrigeration systems.
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Is Dichloromethane a greenhouse gas?

It has some impact but less than other compounds.
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Is Dichloromethane used in pharmaceuticals?

Yes, in the production of some drugs.
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What precautions are needed when handling Chloroform?

Use in a well-ventilated area and avoid skin contact.
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Can Chloroform be detected by its smell?

Yes, it has a distinct sweet smell.
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Is Dichloromethane flammable?

It's less flammable than many organic solvents.
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Is Dichloromethane regulated by environmental agencies?

Yes, due to its potential health and environmental impact.
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Can Chloroform be synthesized in a lab?

Yes, through chlorination of methane.
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Does Dichloromethane have a color?

It's a colorless liquid.
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About Author
Shumaila Saeed
Written by
Shumaila Saeed
Shumaila Saeed, an expert content creator with 6 years of experience, specializes in distilling complex topics into easily digestible comparisons, shining a light on the nuances that both inform and educate readers with clarity and accuracy.

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